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An open network of connections and partnerships, to transform knowledge into change

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Research

At the heart of ISI Foundation is interdisciplinary scientific research, with the goal of advancing complex systems science, network science, and data science to address complex socio-technical phenomena and impact public health and sustainable development.

Education

Research grants, European projects, university collaborations: ISI Foundation’s initiatives for a high-level training network.

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Research

At the heart of ISI Foundation is interdisciplinary scientific research, with the goal of advancing complex systems science, network science, and data science to address complex socio-technical phenomena and impact public health and sustainable development.

Community

From the international scientific network to the link with the nonprofit world, ISI Foundation is an active hub between universities, companies, and institutions—committed to facilitating processes of change.

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Education

Research grants, European projects, university collaborations: ISI Foundation’s initiatives for a high-level training network.

Community

From the international scientific network to the link with the nonprofit world, ISI Foundation is an active hub between universities, companies, and institutions—committed to facilitating processes of change.

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Lagrange Project Community

Lagrange Project

The Lagrange Prize

The Lagrange Prize – CRT Foundation is the leading award in the field of Complex Systems Science. Created in 2008, and coordinated by ISI Foundation, the Prize awards internationally renowned scientists advancing complex systems science, data science and their applications. The Lagrange Prize Awardees comprise a world-class group of scientists, thought leaders and communicators, including Nobel laureates.

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Lagrange Project Education

Lagrange Project

Lagrange Scholarships

The Lagrange Project supports the training of a new generation of young talents in the applications of complex systems science, data science, and artificial intelligence to societal challenges and sustainable development. The program provides a yearly cohort of scholarships, the Lagrange Scholarships, that support selected, freshly graduated STEM students and offers them a one year experiential learning path.

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Lagrange Project Research

Lagrange Project

Lagrange Laboratory

CRT Foundation, a co-founding partner and main funder of the institute, supports the work of ISI Foundation through a targeted initiative, the Lagrange Project, that comprises research, training and community building actions. The research and innovation component of the Lagrange Project is the Lagrange Laboratory and is organized in four broad interdisciplinary areas: Computational and Digital Epidemiology, Computational Social Science, Data for Social Impact and Sustainability, Complex Systems and Data Science.

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Projects

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EvoGamesPlus

Evolutionary games and population dynamics: from theory to applications
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Influenzanet & Influweb

Influenzanet is a system designed to monitor the activity of influenza-like-illness (ILI) with the aid of volunteers via the Internet.
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VERDI

VERDI – SARS-coV2 variants Evaluation in pRegnancy and paeDIatrics cohorts

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STAMINA

STAMINA develops an intelligent decision support toolset for pandemic prediction and management and demonstrates its use by practitioners at national and regional levels within and across EU borders.
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The Lagrange Project

Lagrange Project

The mission of the ISI Foundation has been generously supported since its inception by the CRT Foundation. Since 2003, the support of the CRT Foundation has been organized under the umbrella of the Lagrange Project, a comprehensive initiative on complex systems, data science, and its societal applications, that includes a scholarship program and a renowned prize.

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Latest publications

Network ScienceOther
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Social interactions in isolated, confined, and extreme environments: A study of Antarctic winter teams using wearable sensors

Andrea Cantisani, Jan B. Schmutz, Pedro Marques-Quinteiro, Lorenzo Dall’Amico, Ciro Cattuto, Mirko Antino, Walter J. Eppich, Katharina Stegmayer, Sebastian Walther
PNAS123 (22), e2533420123 (2026)
Data ScienceHealth
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Global approaches to infectious disease surveillance and modeling

Mark P. Khurana, Joseph L -H Tsui, Bernardo Gutierrez, Ayush Chopra, Neil Scheidwasser, Harrison Bo Hua Zhu, Serina Y. Chang, David A. Duchêne, Cathal Mills, Rhys P D Inward, Benjamin Reddy, John Brittain, Abhishek Dasgupta, James Sheldon, George Githinji, John S. Brownstein, Mélodie Monod, Luca Ferretti, Sivan Bershan, Simon Tietze, Leonardo Adrian Ferres, Silvia Argimón, Timothy J. Dallman, Etien Koua, Oliver Ratmann, Simon Cauchemez, Lauren Ancel Meyers, Lili Su, Alessandro Vespignani, Paul Pronyk, Áine O’Toole, Andrew Rambaut, Nicholas J. Loman, Edward C. Holmes, Seth Flaxman, Nicola Mulder, Oliver W. Morgan, Houriiyah Tegally, Manuel Gomez-Rodriguez, Nigel Shadbolt, Christian Happi, Meera Chand, Sofonias K. Tessema, Placide Mbala-Kingebeni, Marc A. Suchard, Oliver G. Pybus, Samuel V. Scarpino, Samir Bhatt, Moritz U. G. Kraemer
Nature Medicine32, 1646–1660 (2026)
Network ScienceOther
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Modeling memory in time-respecting paths on temporal networks

Silvia Guerrini, Ciro Cattuto, Lorenzo Dall’Amico
EPJ Data Science (2026)
Health
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Nontraditional Data in Pandemic Preparedness and Response: Identifying and Addressing First- and Last-Mile Challenges

Mattia Mazzoli, Irma Varela-Lasheras, Sònia Namorado, Constantino Pereira Caetano, Andreia Leite, Lisa Hermans, Niel Hens, Polen Türkmen, Kyriaki Kalimeri, Leonardo Adrian Ferres, Ciro Cattuto, Daniela Paolotti, Stefaan G. Verhulst
Journal of Medical Internet Research28, e85540 (2026)
HealthNetwork Science
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Small-world scale-free brain networks from EEG with application to motor imagery decoding and brain fingerprinting

Mohammad Davood , Vahid Abootalebi, Hamid Saeedi-Sourck, Andrea Santoro, Harry H. Behjat
Computers in Biology and Medicine206, 111606 (2026)
Health
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Relationship between household attributes and contact patterns in urban and rural South Africa

Kausutua Tjikundi, Jackie Kleynhans, Stefano Tempia, Cheryl Cohen, Daniela Paolotti, Ciro Cattuto, Lorenzo Dall’Amico
PLoS One21(3), e0344732 (2026)
Computational Social ScienceSustainable Development
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Mapping regional disparities in discounted grocery products

Antonio Desiderio, Alessia Galdeman, Franziska Bäuerlein, Sune Lehmann
npj Science of Food10, Art. No. 112 (2026)
Computational Social Science
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Language-Agnostic Modeling of Source Reliability on Wikipedia

Jacopo D’Ignazi, Andreas Kaltenbrunner, Yelena Mejova, Michele Tizzani, Kyriaki Kalimeri, Mariano Gastón Beiró, Pablo Aragón
ACM Transactions on the Web20, Art. 2, pp- 1-29 (2026)
Health
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Social Structure of Sheep Flocks at Points of the Production Cycle and Relationship to Disease Spread, Using a Simulated Epidemic of Footrot

Katharine E. Lewis, Emily Price, Darren P. Croft, Joss Langford, Laura Ozella, Ciro Cattuto, Rachel Clifton, Laura E. Green
Animals16(4), 587 (2026)
Network ScienceOther
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Social interactions in isolated, confined, and extreme environments: A study of Antarctic winter teams using wearable sensors

Andrea Cantisani, Jan B. Schmutz, Pedro Marques-Quinteiro, Lorenzo Dall’Amico, Ciro Cattuto, Mirko Antino, Walter J. Eppich, Katharina Stegmayer, Sebastian Walther
PNAS123 (22), e2533420123 (2026)
Data ScienceHealth
PDF ↓

Global approaches to infectious disease surveillance and modeling

Mark P. Khurana, Joseph L -H Tsui, Bernardo Gutierrez, Ayush Chopra, Neil Scheidwasser, Harrison Bo Hua Zhu, Serina Y. Chang, David A. Duchêne, Cathal Mills, Rhys P D Inward, Benjamin Reddy, John Brittain, Abhishek Dasgupta, James Sheldon, George Githinji, John S. Brownstein, Mélodie Monod, Luca Ferretti, Sivan Bershan, Simon Tietze, Leonardo Adrian Ferres, Silvia Argimón, Timothy J. Dallman, Etien Koua, Oliver Ratmann, Simon Cauchemez, Lauren Ancel Meyers, Lili Su, Alessandro Vespignani, Paul Pronyk, Áine O’Toole, Andrew Rambaut, Nicholas J. Loman, Edward C. Holmes, Seth Flaxman, Nicola Mulder, Oliver W. Morgan, Houriiyah Tegally, Manuel Gomez-Rodriguez, Nigel Shadbolt, Christian Happi, Meera Chand, Sofonias K. Tessema, Placide Mbala-Kingebeni, Marc A. Suchard, Oliver G. Pybus, Samuel V. Scarpino, Samir Bhatt, Moritz U. G. Kraemer
Nature Medicine32, 1646–1660 (2026)
Network ScienceOther
PDF ↓

Modeling memory in time-respecting paths on temporal networks

Silvia Guerrini, Ciro Cattuto, Lorenzo Dall’Amico
EPJ Data Science (2026)
see all publications ↗