As cities seek to move away from car dependence and towards more sustainable urban living, the need for amenity-rich, walkable, and accessible neighborhoods is greater than ever.  COLINE – Complex Links of Neighbourhoods is at the forefront of rethinking urban spaces by integrating architectural, mobility, and economic considerations into a comprehensive, data-driven approach to urban planning. Inspired by the 15-Minute City framework and supported by the EU Partnership’s Driving Urban Transition (DUT) initiative, COLINE is pioneering new ways to understand and shape cities that are livable, inclusive, and climate-conscious. Through collaborations with Budapest, Copenhagen, Toulouse, Turin, and Vienna, COLINE is developing cutting-edge tools that combine location-based mobile phone data with AI-driven urban perception analysis. By mapping neighborhood amenity compositions, tracing visits, and analyzing multimodal mobility patterns, the project aims to diagnose accessibility, social integration, commuting, and the resilience of neighbourhoods at a fine spatial resolution.